Collier Museum in Naples is worth the trip, if you have time.
There are plenty of similar roads here and there to 66.
In Florida you can easily find stretches of the original Hwy 1. (few hundred feet at a time usually)
In Georgia
The Bruce Weiner Microcar Museum microcars, bmw isetta, messerschmitt, messerschmidt, kr200, micro cars
Nashville
Lane Motor Museum - Nashville, TN